AutismKB

Detailed Information for rs4760816

Basic Information
SNP Name:rs4760816
SNP location:chr12:70658867-70658868
Related Gene:TPH2
Function:intron
Related Studies Statistic
FBATCase controlGWAS FBATGWAS case control
3 1 0 0
Low Scale Association Studies
Family Based Association Studies: 3 results 
Transmission Disequilibrium Test (TDT)
Results #Informative Families Alele Name Transmitted (frequency) Non-Transmitted (frequency) P valueStudy Information
- C
T
119 ( - )
129 ( - )
129 ( - )
119 ( - )
0.525Ramoz,2006_1
  • Ancestral: Caucasian
  • Country: USA, AGRE
  • Diagnosis criteria: ADI-R
  • Final diagnosis: ASD
  • Family : Total Family: 352 Simplex Family: 80 Multiplex Family: 272
  • Affected: All: 650 Women: 141 Age: - Age Range: - IQ:- IQ Range:-
  • Unaffected: All:
OTHERS
Results Alele 1 Alele 2 Statistic Method P value Study Information
C TPDT -Schnetz-Boutaud,2009_1
  • Ancestral: Caucasian
  • Country: USA
  • Diagnosis criteria: DSM-IV, ADI-R
  • Final diagnosis: ASD
  • Family : Total Family: 403 Simplex Family: 252 Multiplex Family: 151
  • Affected: All: - Women: - Age: - Age Range: - IQ:- IQ Range:-
  • Unaffected: All:-
C Tothers -Anderson,2009_1
  • Ancestral: Caucasian
  • Country: USA, AGRE
  • Diagnosis criteria: DSM-IV,ADI-R
  • Final diagnosis: ASD
  • Family : Total Family: 403 Simplex Family: 252 Multiplex Family: 151
  • Affected: All: - Women: - Age: - Age Range: (3-21) IQ:- IQ Range:-
  • Unaffected: All:-
Case-Control Based Association Studies: 1 results 
Results Alele Type Genotype P value Study Information
Allele 1 Allele 2 Allele 1/Allele 1 Allele 1/Allele 2 Allele 2/Allele 2

ASD
CTR
C
- (38.80%)
- (39.70%)
T
- (61.2%)
- (60.3%)
C/C
- ( - )
- ( - )
C/T
- ( - )
- ( - )
T/T
- ( - )
- ( - )
-Coon,2005_1
  • Ancestral: Caucasian
  • Country: USA, Italy
  • Diagnosis criteria: ADI-R,ADOS,DSM-IV
  • Final diagnosis: ASD
  • Case description: People:88 Women: 8
  • Age: 13.53
  • IQ: 82.56
  • Control description: People: 95 Women:
Genome-Wide Association Studies
Family Based Association Studies: 0 results 
Case-Control Based Association Studies: 0 results 

Quick Search:


  (e.g. NLGN4X)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
  • Click to Download Data

Registered with NIF