AutismKB

Detailed Information for rs3735653

Basic Information
SNP Name:rs3735653
SNP location:chr7:154944193-154944194
Related Gene:EN2
Function:missense
Related Studies Statistic
FBATCase controlGWAS FBATGWAS case control
4 0 0 0
Low Scale Association Studies
Family Based Association Studies: 4 results 
Transmission Disequilibrium Test (TDT)
Results #Informative Families Alele Name Transmitted (frequency) Non-Transmitted (frequency) P valueStudy Information
- A
G
- ( - )
- ( - )
- ( - )
- ( - )
0.58Zhong,2003_1
  • Ancestral: Caucasian
  • Country: AGRE
  • Diagnosis criteria: ADI-R
  • Final diagnosis: ASD
  • Family : Total Family: 196 Multiplex Family: 196
  • Affected: All: 437 Women: - Age: - Age Range: - IQ:- IQ Range:-
  • Unaffected: All:-
- T
C
75 ( - )
57 ( - )
57 ( - )
75 ( - )
0.1168Gharani,2004_1
  • Ancestral: Caucasian
  • Country: AGRE
  • Diagnosis criteria: ADI-R
  • Final diagnosis: ASD
  • Family : Total Family: 167 Simplex Family: 133 Multiplex Family: 34
  • Affected: All: 167 Women: - Age: - Age Range: - IQ:- IQ Range:-
  • Unaffected: All:-
66 C
T
42 (0.51%)
41 (0.49%)
41 (0.49%)
42 (0.51%)
1Sen,2010_1
  • Ancestral: Caucasian
  • Country: India
  • Diagnosis criteria: DSM-IV, CARS
  • Final diagnosis: ASD
  • Family : Total Family: 128 Simplex Family: 105
  • Affected: All: 128 Women: 22 Age: 5.98 ± 3.1 Age Range: - IQ:- IQ Range:-
  • Unaffected: All:
OTHERS
Results Alele 1 Alele 2 Statistic Method P value Study Information
C Tothers -Wang,2008_1
  • Ancestral: Asian
  • Country: China
  • Diagnosis criteria: DSM-IV,CARS,ABC
  • Final diagnosis: AD
  • Family : Total Family: 210 Simplex Family: 210
  • Affected: All: 210 Women: 14 Age: 6.5 Age Range: (2-17) IQ:- IQ Range:-
  • Unaffected: All:
Case-Control Based Association Studies: 0 results 
Genome-Wide Association Studies
Family Based Association Studies: 0 results 
Case-Control Based Association Studies: 0 results 

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  (e.g. NLGN4X)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
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