AutismKB


Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /rd1/www/autismkb_www/mysql_connect.php on line 14

Detailed Information for rs2268490

Basic Information
SNP Name:rs2268490
SNP location:chr3:8772084-8772085
Related Gene:OXTR
Function:intron
Related Studies Statistic
FBATCase controlGWAS FBATGWAS case control
2 0 0 2
Low Scale Association Studies
Family Based Association Studies: 2 results 
Transmission Disequilibrium Test (TDT)
Results #Informative Families Alele Name Transmitted (frequency) Non-Transmitted (frequency) P valueStudy Information
- T
C
- ( - )
- ( - )
- ( - )
- ( - )
0.25Tansey,2010_1
  • Ancestral: Caucasian
  • Country: Ireland, Portugal, UK
  • Diagnosis criteria: DSM-IV, ADI-R, ADOS-G, VABS
  • Final diagnosis: ASD
  • Family : Total Family: 436 Simplex Family: 436
  • Affected: All: 436 Women: - Age: - Age Range: - IQ:- IQ Range:-
  • Unaffected: All:
OTHERS
Results Alele 1 Alele 2 Statistic Method P value Study Information
C Tothers 0.2695Lerer,2008_1
  • Ancestral: Asian
  • Country: Israel
  • Diagnosis criteria: DSM-IV,ADI-R,ADOS-G,VABS
  • Final diagnosis: ASD
  • Family : Total Family: 133
  • Affected: All: 152 Women: 24 Age: - Age Range: (2.08-33.67) IQ:68.7 IQ Range:-
  • Unaffected: All:
Case-Control Based Association Studies: 0 results 
Genome-Wide Association Studies
Family Based Association Studies: 0 results 
Case-Control Based Association Studies: 2 results 
Results Alele Type Genotype P value Combined P valueStudy Information
Allele 1 Allele 2 Allele 1/Allele 1 Allele 1/Allele 2 Allele 2/Allele 2

ASD
CTR
C
224 (82.00%)
699 (91.00%)
T
48 (18.00%)
67 (9.00%)
-
- ( - )
- ( - )
-
- ( - )
- ( - )
-
- ( - )
- ( - )
0.000059-de Krom,2008_1
  • Ancestral: Caucasian
  • Country: Holland
  • Diagnosis criteria: DSM-IV-TR, ADI-R, ADOS
  • Final diagnosis: ASD
  • Case description: People:144 Women: 25
  • Age range: (4-18)
  • IQ range:30%MR
  • Control description: People: 404 Women:
  • Stage: Discovery

ASD
CTR
C
218 (87.00%)
209 (85.00%)
T
34 (13.00%)
37 (15.00%)
-
- ( - )
- ( - )
-
- ( - )
- ( - )
-
- ( - )
- ( - )
0.6212-de Krom,2008_2
  • Ancestral: Caucasian
  • Country: UK
  • Diagnosis criteria: ICD-10, ADI-R, ADOS
  • Final diagnosis: ASD
  • Case description: People:128 Women: 18
  • Age range: (4-18)
  • IQ range:23%MR
  • Control description: People: 273 Women:
  • Stage: Replication

Quick Search:


  (e.g. NLGN4X)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
  • Click to Download Data

Registered with NIF