AutismKB

Suggested Autism Candidate Gene List

This dataset contains 171 genes.
Using a Core Dataset from review papers, we get a weight matrix.
The comobined score comes from scores from each dataset plus each weight matrix. The higher the score, the more confident the gene is.
Only the genes with total score larger than or equal to 16 (the smallest score of the gene in the core datasset) and level3/level 4 syndromic autism genes are listed below. (More information about the dataset)
Gene ID Gene Symbol Band Evidence Score Total Score
GWAS Expression CNV Linkage Low-Scale Association Other Low-Scale Studies
AutG4128 MAOA Xp11.3 0 0 1 0 1 3 26
AutG4204 MECP2 Xq28 0 0 1 0 1 3 26
AutG85358 SHANK3 22q13.3 0 0 2 0 0 3 25
AutG2558 GABRA5 15q11.2-q12 0 2 3 0 1 2 25
AutG2332 FMR1 Xq27.3 0 1 0 0 1 3 25
AutG2571 GAD1 2q31 0 1 1 2 2 2 25
AutG3778 KCNMA1 10q22.3 0 1 1 1 0 3 25
AutG1977 EIF4E 4q21-q25 0 0 1 1 0 3 24
AutG23705 CADM1 11q23.2 0 1 1 0 0 3 24
AutG140733 MACROD2 20p12.1 3 0 1 0 1 0 23
AutG2925 GRPR Xp22.2 0 0 1 0 0 3 23
AutG1814 DRD3 3q13.3 2 0 0 1 1 1 23
AutG1815 DRD4 11p15.5 0 0 1 0 0 3 23
AutG26053 AUTS2 7q11.22 0 0 1 0 0 3 23
AutG596 BCL2 18q21.33|18q21.3 0 0 1 0 0 3 23
AutG6134 RPL10 Xq28 0 0 1 0 0 3 23
AutG57492 ARID1B 6q25.1 0 0 1 0 0 3 23
AutG11141 IL1RAPL1 Xp22.1-p21.3 0 0 1 0 0 3 23
AutG10716 TBR1 2q24 0 0 1 0 0 3 23
AutG27086 FOXP1 3p14.1 0 0 1 0 0 3 23
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  (e.g. NLGN4X)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
  • Click to Download Data

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