AutismKB

Suggested Autism Candidate Gene List

This dataset contains 171 genes.
Using a Core Dataset from review papers, we get a weight matrix.
The comobined score comes from scores from each dataset plus each weight matrix. The higher the score, the more confident the gene is.
Only the genes with total score larger than or equal to 16 (the smallest score of the gene in the core datasset) and level3/level 4 syndromic autism genes are listed below. (More information about the dataset)
Gene ID Gene Symbol Band Evidence Score Total Score
GWAS Expression CNV Linkage Low-Scale Association Other Low-Scale Studies
AutG5649 RELN 7q22 2 0 0 1 3 3 43
AutG26047 CNTNAP2 7q35 2 0 1 1 2 3 42
AutG5021 OXTR 3p25 1 1 1 1 3 3 40
AutG57502 NLGN4X Xp22.33 2 0 1 0 1 3 38
AutG2562 GABRB3 15q11.2-q12 0 1 3 0 2 3 34
AutG721 C4B 6p21.3 0 2 1 0 3 3 34
AutG4233 MET 7q31 0 1 1 0 3 3 33
AutG93986 FOXP2 7q31 1 0 1 1 1 3 33
AutG3123 HLA-DRB1 6p21.3 0 1 1 0 3 3 33
AutG6532 SLC6A4 17q11.2 0 0 0 2 3 3 32
AutG54715 RBFOX1 16p13.3 2 2 1 2 0 2 32
AutG2020 EN2 7q36 0 0 0 0 3 3 30
AutG627 BDNF 11p13 0 0 1 0 2 3 29
AutG9378 NRXN1 2p16.3 0 0 2 0 1 3 28
AutG4139 MARK1 1q41 0 1 0 0 2 3 28
AutG8604 SLC25A12 2q24 0 2 0 2 3 2 27
AutG26470 SEZ6L2 16p11.2 0 0 3 0 0 3 27
AutG5595 MAPK3 16p11.2 0 0 3 0 0 3 27
AutG54413 NLGN3 Xq13.1 0 0 1 0 1 3 26
AutG438 ASMT Xp22.3 or Yp11.3 0 0 1 0 1 3 26
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
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