Evidence Detail for PRKX
Basic Information Top
| Gene Symbol: | PRKX ( PKX1 ) |
|---|---|
| Gene Full Name: | protein kinase, X-linked |
| Band: | Xp22.3 |
| Quick Links | Entrez ID:5613; OMIM: 300083; Uniprot ID:PRKX_HUMAN; ENSEMBL ID: ENSG00000183943 |
Sequences Top Evidence Statistic TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
| Evidences | Syndromic Gene | GWAS | Expression | CNV | Linkage | Low Scale Association | Other Studies | Total |
|---|---|---|---|---|---|---|---|---|
| Score (No. of Studies) | No | 2 (2) | 0 (0) | 1 (4) | 0 (0) | 0 (0) | 1 (1) | 21 (3) |
Syndromic Autism Gene TopLow Scale Association Studies (by Ethnic Group) TopGenome-Wide Association Studies(By Ethnic Group) Top Family Based Association Studies: 1
| Reference | Stage | #SNPs/ #VNTRs | #Families | Affecteds | Result | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ (range) |
||||||
| CAUCASIAN | |||||||||||
| Wang, 2009_1 | Discovery | 1 (detail) | 780 | 1299 (-) |  | | ASD | - - |
- - | ||
Case Control Based Association Studies: 1
| Reference | Stage | #SNPs/ #VNTRs | ASD Cases | Normal Controls | Result | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #Subjects (% Women) |
ADI-R | ADOS | Diagnosis | Age (range) |
IQ | #Subjects (% Women) |
Age (range) |
|||||
| CAUCASIAN | ||||||||||||
| Wang, 2009_2 | Discovery | 1 (detail) | 1204 (-) | | | ASD | 10.3±6.6 - |
10.9±6.7 | 6491 (-) |
8.8±5.4 - | ||
Other Low Scale Gene Studies Top| Reference | Orangnism | Tissue | ADI-R | ADOS | Diagnosis | Evidence Level | Result | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Piton, 2010_1 | human | blood |  | | ASD | genetics: mutation screen | ||||
| ||||||||||
Large Scale Expression Studies TopCNV Studies Top| CNV Name | Chr | Band | Gain/Loss | Number of CNVs | Evidence Type | Reference | |
|---|---|---|---|---|---|---|---|
| Case | Control | ||||||
| AutCNV0000161 | X | Xp22.33-22.31 | loss | 1 | - | Denovo CNVs; | Marshall, 2008 |
| AutCNV0000299 | X | Xp22 | loss | 1 | - | Denovo CNVs; | Thomas, 1999 |
| AutCNV0000300 | X | Xp22 | loss | 1 | - | Denovo CNVs; | Thomas, 1999 |
| AutCNV0000301 | X | Xp22 | loss | 1 | - | Denovo CNVs; | Thomas, 1999 |
| AutCNV0000713 | X | Xp11.2-p22.33 | gain | 1 | - | CNVs Only Present In Patients; | Edens, 2011 |
| AutCNV0004398 | X | Xp22.32-p22.33 | loss | 1 | - | CNVs Only Present In Patients; | Sanders, 2011 |
Linkage Studies TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
