AutismKB

Evidence Detail for IL8


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Basic Information Top
Gene Symbol:IL8 ( CXCL8,GCP-1,GCP1,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1,NAP1 )
Gene Full Name: interleukin 8
Band: 4q13-q21
Quick LinksEntrez ID:3576; OMIM: 146930; Uniprot ID:IL8_HUMAN; ENSEMBL ID: ENSG00000169429
Sequences Top
>IL8|3576|nucleotide
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>IL8|3576|protein
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Evidence Statistic Top

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Evidences Syndromic Gene GWAS Expression CNV Linkage Low Scale Association Other Studies Total
Score (No. of Studies) No 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 1 (1) 7 (1)
Syndromic Autism Gene Top
Low Scale Association Studies (by Ethnic Group) Top
Genome-Wide Association Studies(By Ethnic Group) Top
Other Low Scale Gene Studies Top
Reference Orangnism Tissue ADI-R ADOS Diagnosis Evidence Level Result
Suzuki, 2011_1 human blood21 were ASD, 7 were PDD-NOS expression level
  • Subjects: 28
  • Normal Controls: 28
  • Methods: multiplex assay kits
  • Evidence Details: The plasma concentrations of IL-1b, IL-1RA, IL-5, IL-8, IL-12(p70), IL-13, IL-20 and GRO-a were significantly higher in subjects with ASD compared with the corresponding values of matched controls after correction for multiple comparisons.
Large Scale Expression Studies Top
CNV Studies Top
Linkage Studies Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
  • Click to Download Data

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