AutismKB

Evidence Detail for CTNNA3


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Basic Information Top
Gene Symbol:CTNNA3 ( MGC26194,MGC75041,VR22 )
Gene Full Name: catenin (cadherin-associated protein), alpha 3
Band: 10q22.2
Quick LinksEntrez ID:29119; OMIM: 607667; Uniprot ID:CTNA3_HUMAN; ENSEMBL ID: ENSG00000183230
Sequences Top
>CTNNA3|29119|nucleotide
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>CTNNA3|29119|protein
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Evidence Statistic Top

Click the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default.
Evidences Syndromic Gene GWAS Expression CNV Linkage Low Scale Association Other Studies Total
Score (No. of Studies) No 2 (5) 0 (0) 1 (4) 0 (0) 0 (0) 0 (0) 14 (5)
Syndromic Autism Gene Top
Low Scale Association Studies (by Ethnic Group) Top
Genome-Wide Association Studies(By Ethnic Group) Top
Family Based Association Studies: 4
Reference Stage #SNPs/ #VNTRs #Families Affecteds Result
#Subjects
(% Women)
ADI-R ADOS Diagnosis Age
(range)
IQ
(range)
CAUCASIAN
Weiss, 2009_2 Replication 1 (detail) 2073 -
(-)
ASD -
-
-
-
Wang, 2009_1 Discovery 1 (detail) 780 1299
(-)
ASD -
-
-
-
Hussman, 2011_1 Discovery 1 (detail) 597 -
(-)
ASD -
-
-
-
MIXED/OTHERS
Weiss, 2009_1 Discovery 1 (detail) 1038 -
(-)
ASD -
-
-
-
Case Control Based Association Studies: 1
Reference Stage #SNPs/ #VNTRs ASD Cases Normal Controls Result
#Subjects
(% Women)
ADI-R ADOS Diagnosis Age
(range)
IQ #Subjects
(% Women)
Age
(range)
CAUCASIAN
Wang, 2009_2 Discovery 1 (detail) 1204
(-)
ASD 10.3±6.6
-
10.9±6.7 6491
(-)
8.8±5.4
-
Other Low Scale Gene Studies Top
Large Scale Expression Studies Top
CNV Studies Top
CNV Name Chr Band Gain/Loss Number of CNVs Evidence Type Reference
Case Control
AutCNV0000090 10 10q21.3 gain 1 - Overlapping/Recurrent CNVs; Szatmari, 2007
AutCNV0000835 10 10q21.3 loss 1 - maternal Pinto, 2010
AutCNV0000836 10 10q21.3 loss 1 - maternal Pinto, 2010
AutCNV0000837 10 10q21.3 loss 1 - maternal Pinto, 2010
AutCNV0000838 10 10q21.3 loss 1 - maternal Pinto, 2010
AutCNV0001108 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0001109 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0001110 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0001290 10 10q21.3 loss 1 - maternal Pinto, 2010
AutCNV0001974 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0001975 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0001976 10 10q21.3 loss 1 - paternal Pinto, 2010
AutCNV0002750 10 10q21.3 gain 1 - maternal Pinto, 2010
AutCNV0003319 10 10q21.3 loss 1 - CNVs Only Present In Patients; Gai, 2011
AutCNV0003657 10 10q21.3 loss 2 - Overlapping/Recurrent CNVs; paternal Gai, 2011
AutCNV0003658 10 10q21.3 loss 1 - CNVs Only Present In Patients; Gai, 2011
AutCNV0003659 10 10q21.3 loss 1 - CNVs Only Present In Patients; Gai, 2011
AutCNV0003826 10 10q21.3 loss 1 - Denovo CNVs; Levy, 2011
Linkage Studies Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 616
  • Genes: 3,075
  • SNPs/VNTRs: 3,386
  • CNVs: 4,617
  • Linkage Regions: 158
  • Last Update: 05/25/2012
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