Evidence Detail for SPON2
Basic Information
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| Gene Symbol: | SPON2 ( DIL-1,DIL1,DKFZp686G21139,FLJ16313,FLJ22401,FLJ34460,M-spondin,Mindin ) |
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| Gene Full Name: | spondin 2, extracellular matrix protein |
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| Band: | 4p16.3 |
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| Quick Links | Entrez ID:10417; OMIM: 605918; Uniprot ID:SPON2_HUMAN; ENSEMBL ID: ENSG00000159674 |
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>SPON2|10417|nucleotide
ATGGAAAACCCCAGCCCGGCCGCCGCCCTGGGCAAGGCCCTCTGCGCTCTCCTCCTGGCCACTCTCGGCGCCGCCGGCCAGCCTCTTGGGGGAGAGTCCATCTGT
TCCGCCAGAGCCCCGGCCAAATACAGCATCACCTTCACGGGCAAGTGGAGCCAGACGGCCTTCCCCAAGCAGTACCCCCTGTTCCGCCCCCCTGCGCAGTGGTCT
TCGCTGCTGGGGGCCGCGCATAGCTCCGACTACAGCATGTGGAGGAAGAACCAGTACGTCAGTAACGGGCTGCGCGACTTTGCGGAGCGCGGCGAGGCCTGGGCG
CTGATGAAGGAGATCGAGGCGGCGGGGGAGGCGCTGCAGAGCGTGCACGCGGTGTTTTCGGCGCCCGCCGTCCCCAGCGGCACCGGGCAGACGTCGGCGGAGCTG
GAGGTGCAGCGCAGGCACTCGCTGGTCTCGTTTGTGGTGCGCATCGTGCCCAGCCCCGACTGGTTCGTGGGCGTGGACAGCCTGGACCTGTGCGACGGGGACCGT
TGGCGGGAACAGGCGGCGCTGGACCTGTACCCCTACGACGCCGGGACGGACAGCGGCTTCACCTTCTCCTCCCCCAACTTCGCCACCATCCCGCAGGACACGGTG
ACCGAGATAACGTCCTCCTCTCCCAGCCACCCGGCCAACTCCTTCTACTACCCGCGGCTGAAGGCCCTGCCTCCCATCGCCAGGGTGACACTGGTGCGGCTGCGA
CAGAGCCCCAGGGCCTTCATCCCTCCCGCCCCAGTCCTGCCCAGCAGGGACAATGAGATTGTAGACAGCGCCTCAGTTCCAGAAACGCCGCTGGACTGCGAGGTC
TCCCTGTGGTCGTCCTGGGGACTGTGCGGAGGCCACTGTGGGAGGCTCGGGACCAAGAGCAGGACTCGCTACGTCCGGGTCCAGCCCGCCAACAACGGGAGCCCC
TGCCCCGAGCTCGAAGAAGAGGCTGAGTGCGTCCCTGATAACTGCGTCTAA
« Hide>SPON2|10417|protein
MENPSPAAALGKALCALLLATLGAAGQPLGGESICSARAPAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAERGEAWA
LMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVGVDSLDLCDGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTV
TEITSSSPSHPANSFYYPRLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHCGRLGTKSRTRYVRVQPANNGSP
CPELEEEAECVPDNCV
« Hide Evidence Statistic
TopClick the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default. 
Syndromic Autism Gene
TopLow Scale Association Studies (by Ethnic Group)
Top Family Based Association Studies: 0
| Reference |
Population |
#SNPs/ #VNTRs |
#Families |
Affecteds |
Result |
#Subjects
(% Women) |
ADI-R |
ADOS |
Diagnosis |
Age
(range) |
IQ
(range) |
| No Evidence. |
Case Control Based Association Studies: 0
| Reference |
Population |
#SNPs/ #VNTRs |
ASD Cases |
Normal Controls |
Result |
#Subjects
(% Women) |
ADI-R |
ADOS |
Diagnosis |
Age
(range) |
IQ |
#Subjects
(% Women) |
Age
(range) |
| No Evidence. |
Genome-Wide Association Studies(By Ethnic Group)
Top Family Based Association Studies: 0
| Reference |
Stage |
#SNPs/ #VNTRs |
#Families |
Affecteds |
Result |
#Subjects
(% Women) |
ADI-R |
ADOS |
Diagnosis |
Age
(range) |
IQ
(range) |
| No Evidence. |
Case Control Based Association Studies: 0
| Reference |
Stage |
#SNPs/ #VNTRs |
ASD Cases |
Normal Controls |
Result |
#Subjects
(% Women) |
ADI-R |
ADOS |
Diagnosis |
Age
(range) |
IQ |
#Subjects
(% Women) |
Age
(range) |
| No Evidence. |
Other Low Scale Gene Studies
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| Reference |
Orangnism |
Tissue |
ADI-R |
ADOS |
Diagnosis |
Evidence Level |
Result |
| No Evidence. |
Large Scale Expression Studies
Top Microarray Studies: 3
| Reference |
Population |
Tissue |
#Subjects
(% Women) |
ADI-R |
ADOS |
Endo- pheno |
Diagnosis |
Normal Controls
(% Women) |
Fold Change |
Up/ Down |
P/Q value |
| Gregg, 2008_1 |
mixed |
lymphoblastoid cell lines |
35
(14.29%) |  | | autism | autism |
12
(25.00%) |
2.113 |
Up |
0.00962 | |
- Platform: U133 Plus 2.0 GeneChip (Affymetrix,Santa Clara, CA, USA)
- ProbeSet: 218638_s_at
- RefSeq_ID/ EST: NM_012445
- GEO_ID: GSE6575
- Statistic Method: a stringent 1.5-fold unpaired t test with Benjamini
|
| Gregg, 2008_2 |
mixed |
lymphoblastoid cell lines |
17
(11.76%) | | | autism with early onset | autism |
12
(25.00%) |
2.064 |
Up |
0.0319 | |
- Platform: U133 Plus 2.0 GeneChip (Affymetrix,Santa Clara, CA, USA)
- ProbeSet: 218638_s_at
- RefSeq_ID/ EST: NM_012445
- GEO_ID: GSE6575
- Statistic Method: a stringent 1.5-fold unpaired t test with Benjamini
|
| Gregg, 2008_3 |
mixed |
lymphoblastoid cell lines |
18
(16.67%) | | | autism with regression | autism |
12
(25.00%) |
2.016 |
Up |
0.0333 | |
- Platform: U133 Plus 2.0 GeneChip (Affymetrix,Santa Clara, CA, USA)
- ProbeSet: 218638_s_at
- RefSeq_ID/ EST: NM_012445
- GEO_ID: GSE6575
- Statistic Method: a stringent 1.5-fold unpaired t test with Benjamini
|
Proteomics Studies:0
| Reference |
Population |
Tissue |
Platform |
#Subjects
(% Women) |
ADI-R |
ADOS |
Diagnosis |
Normal Controls(% Women) |
| No Evidence. |
CNV Studies
TopLinkage Studies
TopContact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
