Evidence Detail for HRAS Basic Information
Top Gene Symbol: HRAS ( C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,K-RAS,N-RAS,RASH1 ) Gene Full Name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog Band: 11p15.5 Quick Links Entrez ID:3265 ; OMIM: 190020 ; Uniprot ID:RASH_HUMAN ; ENSEMBL ID: ENSG00000174775
>HRAS|3265|nucleotide
ATGACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACT
ATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAG
TACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGAC
TCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCC
TACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACCCTCCTGAT
GAGAGTGGCCCCGGCTGCATGAGCTGCAAGTGTGTGCTCTCCTGA
« Hide >HRAS|3265|protein
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKD
SDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS
« Hide Evidence Statistic
Top Click the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default .Syndromic Autism Gene
Top Abbreviations: AD, autosomal dominant; AR, autosomal recessive; ASD, autism spectrum disorder; ID, intellectual disability; XL, X linked. Inheritance AD OMIM Costello syndrome (218040 ) Description Costello syndrome Reference(s) 16443854 ; Level Level 1: The gene has only been reported in single cases with ASD/autistic features. Additional evidences are needed.
Low Scale Association Studies (by Ethnic Group)
Top Family Based Association Studies: 0
Reference
Population
#SNPs/ #VNTRs
#Families
Affecteds
Result
#Subjects
ADI-R
ADOS
Diagnosis
Age
IQ
No Evidence.
Case Control Based Association Studies: 0
Reference
Population
#SNPs/ #VNTRs
ASD Cases
Normal Controls
Result
#Subjects
ADI-R
ADOS
Diagnosis
Age
IQ
#Subjects
Age
No Evidence.
Genome-Wide Association Studies(By Ethnic Group)
Top Family Based Association Studies: 0
Reference
Stage
#SNPs/ #VNTRs
#Families
Affecteds
Result
#Subjects
ADI-R
ADOS
Diagnosis
Age
IQ
No Evidence.
Case Control Based Association Studies: 0
Reference
Stage
#SNPs/ #VNTRs
ASD Cases
Normal Controls
Result
#Subjects
ADI-R
ADOS
Diagnosis
Age
IQ
#Subjects
Age
No Evidence.
Other Low Scale Gene Studies
Top
Reference
Orangnism
Tissue
ADI-R
ADOS
Diagnosis
Evidence Level
Result
Herault, 1993_1 -
- - - -
genetics Positive
Subjects: -
Normal Controls: -
Methods: restriction fragment length polymorphisms
Evidence Details: We report a positive association between autism and the locus containing the gene for HRAS-1.
Herault, 1995_1 -
- - - -
genetics Positive
Subjects: -
Normal Controls: -
Methods: -
Evidence Details: We report a positive association between autism and two HRAS markers, the 3' marker used in the initial study and an additional marker in exon 1.
Kelleher lii, 2012_1 human
blood ASD
Mutation screen Negative
Subjects: 290
Normal Controls: 300
Methods: direct sequencing
Evidence Details: 1 functional rare mutation was found in ASD case, 0 in control
Large Scale Expression Studies
Top Microarray Studies: 0
Reference
Population
Tissue
#Subjects
ADI-R
ADOS
Endo- pheno
Diagnosis
Normal Controls
Fold Change
Up/ Down
P/Q value
No Evidence.
Proteomics Studies:0
Reference
Population
Tissue
Platform
#Subjects
ADI-R
ADOS
Diagnosis
Normal Controls(% Women)
No Evidence.
CNV Studies
Top Linkage Studies
Top
Linkage Name
Band
Chr
Marker
LOD
NPL
P_Value
Reference
No Matched Linkage Regions !
Contact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.
Basic Information Top
Low Scale Association Studies (by Ethnic Group) Top
