Evidence Detail for HRAS Basic Information
Top Gene Symbol: HRAS ( C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,K-RAS,N-RAS,RASH1 ) Gene Full Name: v-Ha-ras Harvey rat sarcoma viral oncogene homolog Band: 11p15.5 Quick Links Entrez ID:3265 ; OMIM: 190020 ; Uniprot ID:RASH_HUMAN ; ENSEMBL ID: ENSG00000174775
>HRAS|3265|nucleotide
ATGACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACT
ATAGAGGATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAG
TACATGCGCACCGGGGAGGGCTTCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATCAAACGGGTGAAGGAC
TCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCC
TACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACCCTCCTGAT
GAGAGTGGCCCCGGCTGCATGAGCTGCAAGTGTGTGCTCTCCTGA
« Hide >HRAS|3265|protein
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKD
SDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPGCMSCKCVLS
« Hide Evidence Statistic
Top Click the link of the category-specific score to view different category of evidences. The categories without any evidences are hidden by default .Syndromic Autism Gene
Top Abbreviations: AD, autosomal dominant; AR, autosomal recessive; ASD, autism spectrum disorder; ID, intellectual disability; XL, X linked. Inheritance AD OMIM Costello syndrome (218040 ) Description Costello syndrome Reference(s) 16443854 ; Level Level 1: The gene has only been reported in single cases with ASD/autistic features. Additional evidences are needed.
Low Scale Association Studies (by Ethnic Group)
Top Family Based Association Studies: 0
Reference
Population
#SNPs/ #VNTRs
#Families
Affecteds
Result
#Subjects (% Women)
ADI-R
ADOS
Diagnosis
Age (range)
IQ (range)
No Evidence.
Case Control Based Association Studies: 0
Reference
Population
#SNPs/ #VNTRs
ASD Cases
Normal Controls
Result
#Subjects (% Women)
ADI-R
ADOS
Diagnosis
Age (range)
IQ
#Subjects (% Women)
Age (range)
No Evidence.
Genome-Wide Association Studies(By Ethnic Group)
Top Family Based Association Studies: 0
Reference
Stage
#SNPs/ #VNTRs
#Families
Affecteds
Result
#Subjects (% Women)
ADI-R
ADOS
Diagnosis
Age (range)
IQ (range)
No Evidence.
Case Control Based Association Studies: 0
Reference
Stage
#SNPs/ #VNTRs
ASD Cases
Normal Controls
Result
#Subjects (% Women)
ADI-R
ADOS
Diagnosis
Age (range)
IQ
#Subjects (% Women)
Age (range)
No Evidence.
Other Low Scale Gene Studies
Top
Reference
Orangnism
Tissue
ADI-R
ADOS
Diagnosis
Evidence Level
Result
Herault, 1993_1
-
- - - -
genetics Positive
Subjects: -
Normal Controls: -
Methods: restriction fragment length polymorphisms
Evidence Details: We report a positive association between autism and the locus containing the gene for HRAS-1.
Herault, 1995_1
-
- - - -
genetics Positive
Subjects: -
Normal Controls: -
Methods: -
Evidence Details: We report a positive association between autism and two HRAS markers, the 3' marker used in the initial study and an additional marker in exon 1.
Kelleher lii, 2012_1
human
blood ASD
Mutation screen Negative
Subjects: 290
Normal Controls: 300
Methods: direct sequencing
Evidence Details: 1 functional rare mutation was found in ASD case, 0 in control
Large Scale Expression Studies
Top Microarray Studies: 0
Reference
Population
Tissue
#Subjects (% Women)
ADI-R
ADOS
Endo- pheno
Diagnosis
Normal Controls (% Women)
Fold Change
Up/ Down
P/Q value
No Evidence.
Proteomics Studies:0
Reference
Population
Tissue
Platform
#Subjects (% Women)
ADI-R
ADOS
Diagnosis
Normal Controls(% Women)
No Evidence.
CNV Studies
Top Linkage Studies
Top
Linkage Name
Band
Chr
Marker
LOD
NPL
P_Value
Reference
No Matched Linkage Regions !
Contact Us if you are an author of a study regarding this gene and do not find your study in this table or find errors in the representation of your study details.