AutismKB

Annotation Detail for ST8SIA2


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Basic Information Top
Gene Symbol:ST8SIA2 ( HsT19690,MGC116854,MGC116857,SIAT8B,ST8SIA-II,STX )
Gene Full Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Band: 15q26
Quick LinksEntrez ID:8128; OMIM: 602546; Uniprot ID:SIA8B_HUMAN; ENSEMBL ID: ENSG00000140557
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139TAS-Golgi membrane-
GO:0005794IEA-Golgi apparatus-
GO:0016020IEA-membrane-
GO:0016021IEA-integral to membrane-
GO:0030173IEA-integral to Golgi membrane-
GO ID Evidence Qualifier GO_term References
GO:0003828TAS-alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity-
GO:0008373TAS-sialyltransferase activity10766765
GO ID Evidence Qualifier GO_term References
GO:0005975TAS-carbohydrate metabolic process10766765
GO:0006464TAS-protein modification process10766765
GO:0006486IEA-protein glycosylation-
GO:0006491TAS-N-glycan processing10766765
GO:0007399TAS-nervous system development9054414
GO:0007411TAS-axon guidance-
GO:0009312TAS-oligosaccharide biosynthetic process10766765
GO:0018279TAS-protein N-linked glycosylation via asparagine-
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
C6orf15ST8SIA211379315466855 Reconstituted Complex
C6orf15ST8SIA211887915466855 Reconstituted Complex
No data
No data
Genomic Variants Top
Variant ID Location Publication Method/platform Gain Lose Total Frequency Sample Size Genes
Variation_87845 chr15:90797350-90798820 19900272 Custom Affymetrix oligonucleotide arrays 0 1 1- 90 Yoruban Individuals for Ibadan Nigeria ST8SIA2
Variant ID Location Publication Method/platform Gain Lose Total Frequency Sample Size Genes
Variation_87846 chr15:90798520-90798820 19900272 Custom Affymetrix oligonucleotide arrays 0 1 1- 90 Yoruban Individuals for Ibadan Nigeria ST8SIA2
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
ST8SIA21126T/C, 19C/T, 27G/T, 621C/G, 851T/C, 907G/C, IVS3+65G/T, IVS5+6C/T, rs2168351, rs3759914, rs3759915, rs3759916, rs3784724, rs3784727, rs3848153, rs3931230, rs8035191 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:106020
  • Data Attributes: MGI curated and HomoloGene calculated
MGI Allele ID Allele Symbol Allele Source Allele Type / Mutant Cell line ID
MGI:3051219St8sia2[tm1Jxm]Allele from Mouse Targeted (knock-out)
  • nervous system phenotype
  • growth/size phenotype
  • behavior/neurological phenotype