AutismKB

Annotation Detail for SAV1


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Basic Information Top
Gene Symbol:SAV1 ( SAV,WW45,WWP4 )
Gene Full Name: salvador homolog 1 (Drosophila)
Band: 14q13-q23
Quick LinksEntrez ID:60485; OMIM: 607203; Uniprot ID:SAV1_HUMAN; ENSEMBL ID: ENSG00000151748
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus19212654
GO:0005737IDA-cytoplasm19212654
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16930133
GO:0042802IPI-identical protein binding16930133
GO ID Evidence Qualifier GO_term References
GO:0007165IEA-signal transduction-
GO:0035329ISS-hippo signaling cascade-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SAV1SFN10907215778465 Affinity Capture-MS
SAV1SFN12191715778465 Affinity Capture-MS
SAV1STK311266420562859 Affinity Capture-MS
SAV1STK312191720562859 Affinity Capture-MS
SAV1STK412191720562859 Affinity Capture-MS
SAV1STK411266520562859 Affinity Capture-MS
No data
No data
Genomic Variants Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927144
  • Data Attributes: MGI curated and HomoloGene calculated
MGI Allele ID Allele Symbol Allele Source Allele Type / Mutant Cell line ID
MGI:3790763Sav1[tm1Dlim]Allele from Mouse Targeted (knock-out)
  • tumorigenesis
  • homeostasis/metabolism phenotype
  • growth/size phenotype
  • endocrine/exocrine gland phenotype
  • embryogenesis phenotype
  • digestive/alimentary phenotype
  • respiratory system phenotype
  • vision/eye phenotype
MGI:4430538Sav1[tm1.1Rjo]Allele from Mouse Targeted (Floxed/Frt)
  • tumorigenesis
  • liver/biliary system phenotype
MGI:4457496Sav1[tm2.1Dlim]Allele from Mouse Targeted (Floxed/Frt)
  • tumorigenesis
  • liver/biliary system phenotype
MGI:4838640Sav1[tm1.1Dupa]Allele from Mouse Targeted (Floxed/Frt)
  • endocrine/exocrine gland phenotype
  • digestive/alimentary phenotype
MGI:4434120Sav1[tm1a(EUCOMM)Wtsi]Mutant from cell lines70077
-
MGI:4434411Sav1[tm1e(EUCOMM)Wtsi]Mutant from cell lines70077
-
MGI:4451736Sav1[tm1a(EUCOMM)Hmgu]Mutant from cell lines70077
-
MGI:4451902Sav1[tm1e(EUCOMM)Hmgu]Mutant from cell lines70077
-